CARDIOLOGY

Gabriel Habib, Sr., M.S., M.D., F.A.C.C., F.C.C.P., F.A.H.A.
Her blood pressure was on the low side. I felt her pulse in the carotid artery in her neck; it was weak, difficult  to detect. Unlike  the usual thumping carotid artery,  her pulse  rose only  reluctantly  to the examining  finger.  At  the  base  of  her  neck,  on  the  chest  wall,  there  was  an  easily  felt  shudder,  a rough vibration with each pulse, like a cat’s purr. When I listened to her heart,  . . . I heard a gruff,
harsh sound like the clearing of a throat.  . . . It was no great Oslerian feat of diagnosis on my part to suspect that she had severe aortic stenosis.
John Stone (1936–2008)
“The Long House Calls” from
In the Country of Hearts: Journeys in the Art of Medicine,  1990
PHYSICAL EXAMINATION

1. Explain normal splitting of the second heart sound (S2).
S2 is normally split into aortic (A2) and pulmonic (P2) components caused by the closing of the two respective valves. The degree of splitting varies with the respiratory cycle or physiologic splitting. With inspiration, the negative intrathoracic pressure leads to increased venous return to the right side of the heart and a decrease to the left side. The increased venous return to the right atrium (RA) causes P2 to occur slightly later and A2 to occur slightly earlier, leading to a widening of the S2 split. With expiration, the negative intrathoracic pressure is eliminated and A2 and P2 occur almost simultaneously. The largest contributor
to the physiologic third heart sound (S3) split is the respiratory variation in the timing of
the pulmonic closure sound.

MEDICAL CONSULTATION

Eric I. Rosenberg, M.D., M.S.P.H., F.A.C.P.

1.   Why do physicians request medical consultation?
& For assistance in making a diagnosis in a patient with symptoms and signs suggestive of an unknown disease or syndrome
& To obtain advice on specific disease management (such as diabetes or hypertension)
& To obtain a procedure usually performed by a subspecialist (e.g., coronary angiogram in a  patient with persistent angina)
& To evaluate a patient’s ability to safely undergo surgical procedures

2.  How can one assess the effectiveness of medical consultation?
& Is the consultation question answered?
& Does the patient benefit from disease improvement or promotion of better long-term health?
& Are the consultant’s recommendations actually implemented?

3.  What factors increase the likelihood that the consultant’s recommendations
    will be ignored  by the referring physician?

& Poor communication between the requesting physician and the consultant (occurring 12–24% of the time in some studies)
& Delayed response to the consultation request
& Failure to address the requesting physician’s key clinical question
& Prematurely ending the consultant’s involvement in the patient’s care
& Infrequent follow-up visits
Goldman L, Lee T, Rudd P: Ten commandments for effective consultation, Arch Intern Med  143:     1753–1755, 1983.

Horwitz RI, Henes CG, Horwitz SM: Developing strategies for improving the diagnostic and management efficacy of medical consultations, J Chronic Dis  36:213–218, 1983.

GENERAL MEDICINE AND AMBULATORY CARE

LISTENING TO THE PATIENT

1.  What interviewing skills can help the physician identify all the significant issues to the patient during the visit?
Remaining open-ended and encouraging the patient to “go on” until all the pertinent issues
have been expressed by the patient. Other facilitative techniques to keep the patient talking
include a simple head nod or saying, “and,” or “what else?” Continue these facilitative
techniques until the patient says, “nothing else.” During the opening of the interview, the
physician should listen to the patient’s “list” of the concerns for that visit, without focusing on
specific signs and symptoms at that time. Physicians too often interrupt the patient and
direct the remaining interview, only focusing on what the physician deems important.
A patient may have other, significant issues that are not immediately expressed, and the
physician may miss this “hidden agenda” if the patient is interrupted. Once the patient has
listed the concerns, the patient and physician can then decide which ones will be addressed.



2.  How can the physician understand more clearly what the patient is trying to describe?
By rephrasing the response in the physician’s words or simply restating what the patient said.
Sometimes the physician simply needs to ask, “Can you find other words to describe your
pain?” Emotional responses and pain are particularly difficult to put into words.

3.  What questions help characterize a symptom?
& Where does the symptom occur?
& What does it feel like?
& When does the symptom occur?
& How is it affected by other things you do?
& Why does the symptom occur (what brings the symptom on)?
 & What makes the symptom better?

4.   Define “sensitivity” and “specificity” of tests.

&  Sensitivity: The percentage of patients who have the disease that is being tested and have
a positive test result
&  Specificity: The percentage of patients who do not have the disease and have a negative
test result


5.   What are the positive and negative predictive values of tests?
&  Positive predictive value: The percentage of patients who have a positive test and have
the disease that is being tested
&  Negative predictive value: The percentage of patients who have a negative test and do not
have the disease


6.   How are these values calculated?
See Figure 2-1.

 Figure 2-1. Calculation of sensitivity, specificity, and predictive value.

7.   What is the NNT?
The number needed to treat that quantifies the number of patients who will require treatment with
a therapy (and who will have no benefit) in order to ensure that at least one of the adverse
events that the therapy should prevent does not occur. Most publications now include this number.
There is no absolute NNT that is appropriate for all therapeutic decisions, but it will depend on
the risks of the therapy, the benefits of treatment, and the patient’s goals for treatment.

MEDICAL ETHICS

William L. Allen, M.Div., J.D.

ETHICAL PRINCIPLES AND CONCEPTS

1. Define the following terms in relation to the patient and physician-patient
relationship: “beneficence,” “nonmaleficence,” and “respect for autonomy.”
& The concept that the physician will contribute to the welfare of the patient
through the recommended medical interventions
& An obligation for the physician not to inflict harm upon the patient
& The obligation of the physician to honor the patient’s right to accept or refuse a
recommended treatment, based on respect for persons

2. What is fiduciary duty?
A duty of trust imposed upon physicians requiring them to place their patients’ best interests
ahead of their own interests.

3. What is conflict of interest?
A situation in which one or more of a professional’s duties to a client or patient conflicts wi
the professional’s self interests, or when a professional’s roles or duties to more than one
patient or organization are in tension or conflict.

4. How should conflicts of interest be addressed?
 Avoided, if possible
 Disclosed to institutional officials or to patients affected
 Managed by disinterested parties outside the conflicted roles or relationships

5. What is conscientious objection?
Objection to participation in or performance of a procedure or test grounded on a person’s
sincere and deeply held belief that it is morally wrong.

6. What is a conscience clause?
A provision in law or policy that allows providers with conscientious objections to decline participati
in activities to which they have moral objections, under certain conditions and limitations.

7. Describe futility.
The doctrine that physicians are not required to attempt treatment if there will be no medical
benefit from it. This has become a very controversial term in recent times, in part because of
inconsistency in definition and usage. In its clearest sense, it is not so controversial. For
example, when the substance laetrile, derived from apricot pits, was rumored to be a cure
for cancer in the early 1970s, desperate cancer patients besieged their physicians to give them this drug. Most physicians in this country declined to do so on the grounds that such a
treatment would be futile and the exercise of professional autonomy warranted refusal of their
patients’ requests in this case. Futility is sometimes inappropriately invoked when the chance
of a treatment’s efficacy is significantly limited, but not zero, and the physician determines that
minimal chance of efficacy to be “futile.”


INFORMED CONSENT


8. How should one request “consent” from a patient?
Consent is not a transitive verb. Sometimes a medical student or resident is instructed to
“go consent the patient.” This implies that consent is an act that a health professional
performs upon a passive recipient who has no role in the action other than passive acceptance.
A health professional seeking consent from a patient should be asking the patient for either an
affirmative endorsement of an offered intervention or a decision to decline the proposed
intervention.

9.   What is consent or mere consent?
Consent alone, without a sufficiently robust level of information to justify the adjective
“informed.” Although  “mere consent” may avoid a finding of battery (which is defined as
physical contact with a person without that person’s consent), it is usually insufficient
permission for the physician to proceed with a procedure or treatment.

10.   What is informed consent?
Consent from a patient that is preceded by and based on the patient’s understanding of the
proposed intervention at a level that enables the patient to make a meaningful decision about
endorsement or refusal of the proposed intervention.


11.   What are the necessary conditions for valid informed consent?
- Disclosure of relevant medical information by health care providers
- Comprehension of relevant medical information by patient (or authorized representative)
-Voluntariness (absence of coercion by medical personnel or institutional pressure)